Key Points

Question  What are the independent and joint associations of daily sitting time and physical activity with mortality outcomes among cancer survivors in the US?

Findings  This prospective cohort study included 1535 cancer survivors followed up for a median of 4.5 years and found that those with a higher sitting time had an increased risk of all-cause, cancer, and noncancer mortality. The highest risk was among those who were inactive or insufficiently active, with sitting time of more than 8 hours per day.

Meaning  The findings of this cohort study suggest that the combination of prolonged sitting and lack of physical activity, highly prevalent among US cancer survivors, is associated with heightened risks of mortality outcomes.


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